Hijack This Log:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\Sygate Firewall\SPF\smc.exe
C:\WINDOWS\system32\spoolsv.exe
C:\Program Files\Avast Antivirus\aswUpdSv.exe
C:\Program Files\Avast Antivirus\ashServ.exe
C:\WINDOWS\Explorer.EXE
C:\WINDOWS\System32\hkcmd.exe
C:\PROGRA~1\AVASTA~1\ashDisp.exe
C:\PROGRA~1\AVASTA~1\ashmaisv.exe
C:\Documents and Settings\All Users\Start Menu\Programs\Startup\winlgn.exe
C:\Documents and Settings\Owner\Application Data\Microsoft\Internet Explorer\Quick Launch\HijackThis.exe

R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Bar = http://mypoiskovik.com/sp.htm
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = http://mypoiskovik.com/index.htm
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://mypoiskovik.com/index.htm
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant = http://mypoiskovik.com/sp.htm
R1 - HKCU\Software\Microsoft\Internet Explorer\SearchURL,(Default) = http://mypoiskovik.com/index.htm
O2 - BHO: (no name) - {02478D38-C3F9-4efb-9B51-7695ECA05670} - C:\Program Files\Yahoo!\Companion\Installs\cpn\ycomp5_3_16_0.dll
O2 - BHO: (no name) - {53707962-6F74-2D53-2644-206D7942484F} - C:\Program Files\Spybot Search & Destroy\SDHelper.dll
O3 - Toolbar: &Radio - {8E718888-423F-11D2-876E-00A0C9082467} - C:\WINDOWS\System32\msdxm.ocx
O3 - Toolbar: Yahoo! Companion - {EF99BD32-C1FB-11D2-892F-0090271D4F88} - C:\Program Files\Yahoo!\Companion\Installs\cpn\ycomp5_3_16_0.dll
O4 - HKLM\..\Run: [IgfxTray] C:\WINDOWS\System32\igfxtray.exe
O4 - HKLM\..\Run: [HotKeysCmds] C:\WINDOWS\System32\hkcmd.exe
O4 - HKLM\..\Run: [avast!] C:\PROGRA~1\AVASTA~1\ashDisp.exe
O4 - HKLM\..\Run: [ashMaiSv] C:\PROGRA~1\AVASTA~1\ashmaisv.exe
O4 - HKLM\..\Run: [SmcService] C:\PROGRA~1\SYGATE~1\SPF\smc.exe -startgui
O4 - Global Startup: Microsoft Office.lnk = C:\Program Files\Microsoft Office\Office10\OSA.EXE
O4 - Global Startup: winlgn.exe
O9 - Extra button: AIM (HKLM)